ROLLING CONTACT FATIGUE (RCF) DEFECTS OF RAILS IN JAPANESE RAILWAYS AND ITS MITIGATION STRATEGIES



ISCOM-like Nanoparticles Formulated with Quillaja brasiliensis Saponins Are Promising Adjuvants for Seasonal Influenza Vaccines

Vaccination is the most effective public health intervention to prevent influenza infections, which are responsible for an important burden of respiratory illnesses and deaths each year.Currently, licensed influenza vaccines are mostly split inactivated, although in order to achieve higher efficacy rates, some influenza vaccines contain adjuvants.A

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Advances in the regulatory mechanisms of mTOR in necroptosis

The mammalian target of rapamycin (mTOR), an evolutionarily highly conserved serine/threonine protein kinase, plays a prominent role in controlling gene expression, metabolism, and cell death.Programmed cell death (PCD) is indispensable for maintaining homeostasis by removing senescent, defective, or malignant cells.Necroptosis, a type of PCD, reli

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